Particle and fibre toxicology 11, 17 (2014). Size-dependent cytotoxicity of silver nanoparticles in human lung cells: the role of cellular uptake, agglomeration and Ag release. Cellular responses induced by silver nanoparticles: In vitro studies. Mutation Research-Genetic Toxicology and Environmental Mutagenesis 726, 129–135 (2011).Īrora S., Jain J., Rajwade J. Genotoxic effects of silver nanoparticles stimulated by oxidative stress in human normal bronchial epithelial (BEAS-2B) cells. The virus is transmitted not only from an infected doe to her kid in the colostrum and milk, but also by direct contact transmission. These diseases are caused by a group of lentiviruses called the small ruminant lentiviruses (SRLVs). 1721, 77 In addition to causing a demyelinating leukoencephalitis of young goats, this virus causes pneumonitis, arthritis, and mastitis of older adult goats. Maedi-visna and caprine arthritis and encephalitis are economically important viral diseases that affect sheep and goats. Nanosilver: A nanoproduct in medical application. Caprine arthritis encephalitis (CAE) is a multisystem viral disease of goats caused by a lentivirus, a type-C retrovirus that is related to the visna virus of sheep. Controlled Release of Biologically Active Silver from Nanosilver Surfaces. Hence, the present results indicate that intracellular Ag 2S formation, resulting from CSE-mediated H 2S production in microglia, sequesters Ag + ions released from AgNPs, significantly limiting their toxicity, concomitantly reducing microglial inflammation and related neurotoxicity. syndrome / rheumatoid pneumoconiosis : silicosis + rheumatoid arthritis. The disease is characterized by progressive inflammation and persistent synovitis, leading to bone and cartilage destruction, functional incapability, and ultimately disability 2,3. Complications : postasphyxial hypoxic-ischemic encephalopathy (HIE) : Sarnat HB. In addition, AgNPs showed significant anti-inflammatory effects, reducing lipopolysaccharide (LPS)-stimulated ROS, nitric oxide and TNFα production, which translated into reduced microglial toxicity towards dopaminergic neurons. Rheumatoid arthritis (RA) is a type of chronic auto-immune disorder that affects 1 of the adult population. ![]() Furthermore, AgNP-treatment up-regulated microglial expression of the hydrogen sulphide (H 2S)-synthesizing enzyme cystathionine-γ-lyase (CSE). ![]() Analytical microscopy demonstrated internalization and dissolution of AgNPs within microglia and formation of non-reactive silver sulphide (Ag 2S) on the surface of AgNPs. In the present study, the in vitro uptake and intracellular transformation of citrate-capped AgNPs by microglia, as well as their effects on microglial inflammation and related neurotoxicity were examined. In addition, understanding AgNP processing by microglia will allow better prediction of their long term bioreactivity. ![]() Given microglia are implicated in neurodegenerative disorders such as Parkinson's disease (PD), it is important to examine how AgNPs affect microglial inflammation to fully assess AgNP neurotoxicity. However, there is a paucity in studies examining the effect of AgNP on the resident immune cells of the brain, microglia. Silver nanoparticles (AgNP) are known to penetrate into the brain and cause neuronal death.
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![]() Step 3: accept the transfer on the receiving device.Step 2: send the data from the source device and search among its folders or drag them straight to the app.Step 1: install the app on all the devices on which the transfer is going to take place.If you want to know how to send a file, just follow these simple steps: Both devices have to authorize the data transfer, to send and receive files and information. This app works by creating its own network from our smartphone to which we can connect other devices provided that they're not too far away. Up to 200 times faster than a Bluetooth connection.CLONEit function to copy all the phone's contents to another terminal with just one click.Control PowerPoint slideshows from your phone.Transfer photos, videos, music, installed applications, SMS text messages, MMS messages, and videos.Transfer files from Android to other platforms, such as Android, iOS or Windows (7, 8, 8.1 and 10).Transfer files between devices, at full speed and without compatibility problems. We can use SHAREit on our Android by downloading the corresponding APK and we won't have any trouble if we want to use it with other devices, whether Windows, macOS, iPhone or iPad. It's an application with which we can transfer files between devices at great speed without being connected to the same network, without cables, and without Bluetooth, even large-sized files. We usually search for solutions that have to do with Bluetooth connections, cables or apps that share the same WiFi network, with all the inherent problems that they come along with, mainly the necessity to have both devices very nearby. On many occasions, we can also find ourselves in the need to transfer large files between all these devices. With the wide range of devices available nowadays (PC, Mac, smartphones, tablets.) it's common to take our work from one to another depending on our location. Hammer Bro., Koopa Troopa, Koopa Paratroopa, Bullet Bill, Piranha Plantīlooper, Cheep-Cheep, Koopa Troopa, Koopa Paratroopa Koopa Troopa, Goomba, Firebar, Podoboo, False Bowser Jumping Cheep-Cheep, Koopa Troopa, Koopa Paratroopa, Blooper Koopa Troopa, Koopa Paratroopa, Goomba, Piranha Plant (Imported as World 3-2 of Vs. Goomba, Koopa Troopa, Koopa Paratroopa, Piranha Plant Goomba, Koopa Troopa, Piranha Plant, Buzzy Beetleįirebar, Koopa Troopa, False Bowser (Imported as World 1-4 of Vs. Goomba, Koopa Troopa (red and green), Koopa Paratroopa (red and Green), Piranha Plant (green) Podoboo - A fireball that will pop out of lava in castle levels.This game introduces bloopers that can fly in the air, which can be stomped. Blooper - A squid that will try to swim into you, or try to fly into you.In a few levels on land, they will jump high into the air and try to hit you. Cheep Cheep - Found in all underwater levels, these fish will try to swim into you.They are often, but not always, found in pairs. A pair of Koopa brothers that will throw hammers. Bullet Bill - A bullet that will be shot out of a cannon toward you.This game introduces a new red variety that appears starting in World 4, which will continue to move in and out even with Mario or Luigi adjacent to their pipes. The green ones are identical to the ones in Super Mario Bros., and will stay in their pipe if Mario or Luigi are right next to it. Piranha Plant - A carnivorous plant that will pop out of pipes trying to bite you.Buzzy Beetle - A beetle that is like a Koopa Troopa, except the only way to kill it is to knock it off an edge, hit it with a shell, or to ram into it while invincible.They can be defeated with a Koopa or Buzzy Beetle shell, fireball, or Super Star. They have spines on their backs, meaning that you cannot kill them by jumping on them. ![]() Spiny - Spinies are the enemies that Lakitus throw at you.They can be stomped but often fly too high to easily reach. Lakitu - Lakitus are Koopas that sit atop clouds throwing Spinies at you.They will sometimes attack in groups, where you will be able to kill them all while jumping once. Goomba - The most common enemy that will only try to run into you.Like the regular Koopas, these are either red or green. Koopa Paratroopa - A Koopa Troopa with wings that will jump extra high or fly in a straight line.If you jump on them, they will come back out of their shells after a few seconds. ![]() The green ones will walk off platforms while the red ones will turn around. There are two types of them, a green one and a red one.
![]() ![]() You are tasked with rebuilding the universe, bit by bit, or rather Element by Element. *** 3rd best reviewed game on WP7 ! Thanks !!! ![]() ★★★★★ All you Lumia 810 owners out there, do yourself a favor and replace that lame duck camera software that came with the phone. ★★★★★ I am genuinely impressed with just how brilliant this application is. ★★★★★ Beautiful app, love the design and filters! ★★★★★ What an app! This allows absolute control over the camera and is a quality app. ★★★★★ Amazing app showcasing the Nokia imaging SDK You also have a favorite button which you can use for one of your favorite actions. 8 modes: Manual, Program, Portrait, Macro, Scenic, Custom 1-3 Pick photo from library menu item in the photo viewer Grids: Rule of thirds, golden ratio, square, Golden spiral High resolution support (Nokia Lumia 1020/1520) Fun effects (Mirror, Mono colors and more) Real-time filter effects (Vintage, Nashville, Green Pop, 1977, Lomo, Early Bird, Valencia, Amaro, Hudson and more) It containts a fully featured photo editor that allows to edit effects of existing photos and to undo effects of photos that have been taken by OneShot OneShot combines real-time photo effects with photo editing. Apply a change, such as a filter, and you can see the difference on your screen in real time. OneShot is a professional mobile camera app and offers high quality filters in a lovely user interface that is overlaid on top of your viewfinder. Dictionary works on tablets and phones and is refreshingly free from annoying ads and paid upgrades. There is also a "word of the day" with our pick of the most interesting and entertaining words in the English language. And we managed to keep data offline without needing a massive app download. It also works well if you only have an intermittent network connection because the definitions are stored offline, locally on the device. You can see your word history and revisit definitions, or make your own list of favourite words to help build up your vocabulary. The speech function helps provide the correct pronunciation. Definitions include synonyms and antonyms which allows the dictionary to also serve as a thesaurus. Wildcard characters can be used to help with word games like crosswords and scrabble where only some of the letters are known, or you have to find an anagram, or with spelling. Then you can follow the links in the definition page to get more word definitions. As you type, Dictionary homes in on the word you are looking for. The home page contains a randomly selected word cloud which will pique your curiosity and help you improve your vocabulary, while the search box allows you to find specific words easily. The dictionary definitions are stored locally, and because it's ad-free there's no need for a network connection. Dictionary is ideal for both native English speakers and English learners or people studying the English language. Dictionary is a free offline English dictionary containing over 200,000 words and definitions and no ads. The men whipped Figueroa and a bodyguard with weapons before the fatal shot, the officials said.Īfter the shooting, the rest of the 30-person VIP crowd scattered. A fistfight broke out between the three men, Figueroa and a bodyguard. One of the three men pulled out a gun and fired a shot into the ground, the newspaper cited authorities as saying. Texas authorities said that, after the concert, three men, apparently intoxicated, began to curse at Figueroa in a VIP area because he would not let them through to his father, according to The Monitor, a McAllen, Texas, newspaper owned by The Register’s parent company, Freedom Communications Inc. Beau Biden, de 46 aos, se encontraba hospitalizado en el. The circumstances of Trigo Figueroa’s death are still unclear, and no arrests have been made. El vicepresidente de Estados Unidos, Joe Biden, anunci este domingo que su hijo mayor, Beau, muri debido a causa de un cncer cerebral. Sebastian has performed in Orange County and Southern California many times, including at venues such as Arrowhead Pond, Staples Center and the Gibson Amphitheatre. He is popular for his mix of Latin pop and ranchera. He’s called “The People’s Poet” and has been a Mexican entertainment icon since the 1970s. He has also won Latin Grammys, including Best Regional Mexican Song and Best Banda Album in 2003. ![]() Sebastian, whose real name is Jose Manuel Figueroa, is famous for songs like “Secreto de Amor” and a recent hit, “Más Allá del Sol.” “He was a very straight-laced man and a real worker,” said uncle Raul Ocampo Figueroa, who lives in Corona. Recently, he spent much of his time at his son’s football practices, friends said. Figueroa also had a young son named Alex. He later worked in Santa Ana at Suave Entertainment, a music management company, and was engaged to be married, friends and family said. He moved to Irvine at age 5, where he lived with his mother, who was Sebastian’s first wife. In front of Figueroa’s home on Monday, a small candle stood next to cards and flowers left by friends and family.įigueroa, the second-oldest of Sebastian’s seven children, helped form his father’s management crew and accompanied the superstar wherever he toured. Don’t leave,” Sebastian cried to his son while holding him, record company officials said.įigueroa died the following day at McAllen Medical Center, officials reported. “He was always by his father’s side for anything and everything,” said Monica Gomez of Lake Forest, who attended Irvine High School with Figueroa.Īuthorities said a gunman fatally shot Figueroa in the back of the head as he tried holding back a swarm of fans after his father’s concert. Family members today are flying his body to a family ranch outside Guerrero, Mexico. Like his dad, Beau was a good, big-hearted, devoutly Catholic and deeply faithful man, who made a difference in the lives of all he touched - and he lives on in their hearts.Those who knew Trigo Figueroa said the 27-year-old Irvine resident died trying to protect his superstar father.įigueroa, the son of iconic Latin singer Joan Sebastian, was gunned down after his father’s concert Saturday night in Mission, Texas. He chased a life of public service, like his dad, serving in Iraq and as Delaware's Attorney General. "He studied the law, like his dad, even choosing the same law school. ![]() Then-president Barack Obama also issued a statement following the tragic loss, commenting on how much like Biden his son was. We know that Beau's spirit will live on in all of us-especially through his brave wife, Hallie, and two remarkable children, Natalie and Hunter. "The entire Biden family is saddened beyond words. "It is with broken hearts that Hallie, Hunter, Ashley, Jill and I announce the passing of our husband, brother and son, Beau, after he battled brain cancer with the same integrity, courage and strength he demonstrated every day of his life," wrote Biden in a statement issued by the White House (via NPR). The American Boat and Yacht Council (ABYC) publishes safety standards for circuit protection, wire sizes and other related issues in electrical systems.Whenever you are working on your electrical system, remove the positive battery cables from the battery terminals to eliminate the chance of a short circuit and/or possible electrocution. Batteries contain a tremendous, and potentially dangerous, amount of stored energy.Since they have lower storage capacity than comparably-sized deep cycles, we recommend them for boats with two identical batteries used interchangeably for starting and house electrical loads.ĭo-it-Yourself: Installing a Battery Charger Most boats with dual-battery systems use one starting battery and one deep cycle battery.ĭual-purpose batteries work well in some applications and are a good compromise because they tolerate deep discharges that would ruin a typical starting battery. Any battery used to power onboard DC loads such as lighting, trolling motors, inverters and other systems should be a quality deep-cycle battery, like our West Marine brand. They are appropriate for sailboats, fishing boats and all other boats with larger DC power requirements. ![]() They are appropriate as the single battery for wakeboard boats, runabouts, personal watercraft and other boats with minimal DC loads where the engine is always running.ĭeep-cycle batteries can endure repeated deep discharging and recharging without damage. They can supply lots of current for a short period of time, but like to be recharged almost immediately and are not tolerant of deep discharges. Starting batteries are similar to automotive batteries. Dual-purpose flooded batteries combine the ability to withstand deep discharges with cranking power to start your engine Still, the only games of this genre that do the raw gameplay better are the ones that snuck their way into this review as a modifier to explain the style of game this is. This is a Diablo-like game that feels a whole lot like Diablo, but doesn’t carve out enough of an identity on its own to leave a lasting impression. It just doesn’t go above and beyond, feeling more generic overall. I wish I had more to say about Torchlight II, because it is a solid dungeon-crawling RPG that features a quality Switch port with some flexible and smart functionality and UI tweaks for the console in both docked and handheld forms. ![]() Disappointingly so, Torchlight II offers no means of local multiplayer on Switch, but four-player online play is present and ran well in my experiences. It doesn’t match up to the variety and expansiveness of Diablo III, but the more focused and uncomplicated scope might make for a nice alternative. This is a totally capable and enjoyable action RPG, likely the second best on the system next to Diablo III. Your enemies are piatas stuffed with gold and gear, and while Runic Games hasnt mastered Blizzards all-encompassing mastery of the incremental and. A lot of options are crammed into a lot of menus, which is sometimes a tiny bit clumsy but rarely confusing. The game is a little hard to get used to but after a while you will get used to it. It’s a welcome sight to see that be a rare blip because Torchlight II on Switch runs extremely well and even features some noticeable UI tweaks for consoles that make the experience much smoother on Switch. The graphics are amazing and the storyline is very interesting. ![]() While Panic Button’s other Switch work (Doom, Wolfenstein, Warframe), have been excellent, I found their Hob port somewhat dodgier. Its an Action RPG in the same vein as the Diablo games - however I would say this game is. The port here is handled by Switch veterans Panic Button, who also handled the Switch port of Hob, Runic Games’ 2017 release. Torchlight II captures all the flavor and excitement of the original game - while expanding the world and adding the features players wanted most, including. Torchlight II is a fantastic addition to the Torchlight series. Overall it’s a somewhat by-the-numbers Diablo-esque RPG that might not be across-the-board exemplary, but it does everything well enough. Originally released in 2012, the version hitting the Switch now in 2019 is a polished experience that translates the quality dungeon crawling of the original release ably on the portable system. The sequel to the first game was originally going to be an MMORPG however Torchlight II was released with both single-player and multi-player support, as the. Torchlight II has a history that owes much to Diablo, both because of its gameplay and some of the original team at the now-defunct Runic Games having ties to Blizzard. ![]() Rich Gang is a full lifestyle apparel brand encompassing every apparel category including fashion mix, active-wear, denim, basics and outerwear. We look forward to working on the amazing products that will be developed for Rich Gang and YMCMB." Birdman is an incredible executive and entertainer with a fresh and distinct point of view. Tom Bennett, CEO of Bravado said, " Bravado has built its licensed brands division by partnering with the most creative and unique entrepreneurs and artists in the space. "I am excited to bring elements of my lifestyle to the masses with the Rich Gang, and with Lil Wayne to be able to share the feel of our labels with the YMCMB Apparel brand." As a longtime fashion enthusiast and the architect of the YMCMB lifestyle, it makes perfect sense to partner with the esteemed Bravado and move into fashion and launch my apparel brands," said Birdman. "As a business owner, I have expanded my portfolio into many different arenas, including spirits and tech. Birdman's Cash Money Records which has sold over 500 million units globally will launch both brands at the respected Agenda Trade Show, held August 19 th – 20 th, in Las Vegas, NV. 19, 2013 /PRNewswire/ - In a partnership with leading music merchandising company Bravado, Cash Money Records and Cash Money Content co-CEO and co-founder, Bryan "Birdman" Williams is proudly moving into the fashion and retail industry with the launch of two apparel brands: Rich Gang & YMCMB. ![]() ![]() Head to the MySMS website to install the app for Chrome, Windows or Mac–or just visit –and log in with your phone number and the password you created. Setup: Install the MySMS app on your Android phone, hit the “Activate” button and create a password. Just visit your Google security settings page, click “Edit” under “authorizing applications and sites,” and click “Revoke Access” for MightyText.ĭownsides: At the moment, there’s still a waiting period to get into the beta, and although MightyText can store messages for up to six months, it doesn’t show your entire text messaging history. MightyText is also easy to cut off from your Google account if you don’t want to use it anymore. ( MORE: Poll Finds Average Teen, Like, Totally Sends 60 Texts a Day) Head to /app and enter time-june1 as the one-time passcode.) ( UPDATE: MightyText has provided an early beta access code for Techland readers. The app can also alert you to incoming calls, which is useful if your phone’s in another room. What’s Neat About It: If you’re going to use MightyText, sign up for the web app beta, which offers a cleaner interface, MMS support for attaching photos from your PC, group messaging, message search and support for other browsers besides Chrome. Install the MightyText app in Google’s Chrome browser, and click on the newly-created icon in the top-right corner of the browser, then sign in using your Google account. Setup: Install the MightyText app on your Android phone, select the Google account you want to use, and tap the big “Complete Setup” button. I’ve tried a bunch of free Android apps that let you send and receive SMS messages on a PC, and have whittled the list down to three favorites: Trust your text messages to a third-party app, and you’ll be able to read incoming texts while your phone remains in your pocket, and respond with all the speed that a full-sized computer keyboard allows. Apple does not allow other devices to send or display your text messages, and it doesn’t offer this functionality itself, except when the message is an iMessage and the other device is a Mac.įor iPhone users, Apple’s decision amounts to an added safety measure at the expense of convenience. Follow someone asks me why an Android phone is worth considering instead of an iPhone, one of the first things I bring up is the ability to send and receive text messages from my PC’s web browser. |